How old are you, really? While your calendar age counts the years since your birth, your biological age reflects the actual health and aging process of your body. In a fascinating discussion on The Aging Games Podcast, Nikolina Lauc, CEO and Co-Founder of GlycanAge, breaks down the science of how we age and, more importantly, how we can take control of it.
What are Glycans?
At the core of the GlycanAge test are glycans—complex sugar molecules that play a vital role in cell-to-cell communication. Unlike dietary sugars, these molecules help regulate our immune system. Specifically, they determine whether our antibodies promote or reduce systemic inflammation. This "inflammaging," or low-grade chronic inflammation, is a key driver of many modern diseases, ranging from cardiovascular issues to autoimmune conditions.
Can You Reverse Your Age?
One of the most empowering takeaways from this conversation is that while genetics account for about 40% of our aging, the remaining 60% is influenced by epigenetics and lifestyle. This means we have significant control over our internal clock. Key factors that influence this process include:
- Hormonal Balance: Hormone levels, particularly estrogen in both men and women, have a profound impact on biological age. The menopausal transition, for example, can accelerate biological aging if not managed correctly.
- The Power of Psychology: Our mental state is often overlooked. Trauma, grief, and long-term relational stress can dramatically increase biological age. Conversely, finding ways to lower internal pressure and stress—whether through therapy, meditation, or life changes—can help "reverse" your biological age.
- Exercise and Recovery: While movement is a longevity drug, the "no pain, no gain" mentality can backfire. Over-exercising without proper recovery can lead to chronic inflammation. The best approach is to listen to your body and adjust your intensity based on your current stress load.
- Microbiome Health: Emerging evidence suggests that a diet rich in diverse, locally sourced plant fibers supports a healthy gut, which in turn informs the immune system and reduces systemic inflammation.
Taking Action
The GlycanAge test provides more than just a number; it offers actionable insights. By using a simple finger-prick blood test, individuals can identify where their inflammation is coming from and work with practitioners to create a personalized plan. Whether it is adjusting your diet, optimizing your hormones, or addressing emotional stressors, understanding your biological age is a powerful step toward a healthier, more resilient future.
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